Weight Loss Articles and News

Weight Loss and Exercise Improve Liver Disease
Fri Feb 13, 5:42 PM ET

NEW YORK (Reuters Health) - For people with chronic liver disease, losing weight and getting more exercise helps their liver function better and improves their quality of life, new research shows.

The findings, which are reported in the medical journal Gut, are based on a study of 31 overweight patients with liver disease who completed a 15-month weight loss and exercise program. Eighteen patients had hepatitis C and 13 had other types of chronic liver disease.

The program included regular meetings with a dietitian and 2.5 hours of aerobic exercise each week.

During the study period, 21 patients successfully dropped a few pounds and kept the weight off. On average, patients lost about 9 percent of their body weight, Dr. E. Powell, from Princess Alexandra Hospital in Brisbane, Australia, and colleagues note.

The amount of weight loss matched the degree of improvement in liver enzyme levels, a measure of how well the liver is functioning. However, maintaining weight loss was critical, as these enzyme levels rose again in 10 patients who were unable to keep the weight off.

Weight loss also had a beneficial effect on fasting serum insulin levels. Once again, this effect disappeared in subjects who regained their weight, the authors report.

Successful weight loss was linked to significant improvements in both physical and mental components of quality of life, the researchers report.

" This study demonstrates that investment in weight reduction has the ability to reduce risk factors associated with progression of liver disease," the authors note. "These results suggest that treatment of overweight patients should form an important component of management of those with chronic liver disease."

SOURCE: Gut, February 2004.

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By Merritt McKinney

NEW YORK (Reuters Health) - A low-fat diet can help dieters lose weight, but a moderate-fat diet that contains plenty of healthy, plant-based fats may be a better choice for boosting cardiovascular health while shedding pounds, new research suggests.

In a new study, people on low-fat and moderate-fat diets both lost weight, but those on the moderate-fat diet experienced a greater reduction in cardiovascular risk.

" A heart-healthy weight-loss diet should include monounsaturated fats like those found in nuts, seeds, peanut and olive oils," lead author Dr. Christine L. Pelkman of the State University of New York at Buffalo told Reuters Health.

But people should not go overboard on fats and expect to lose weight, Pelkman cautioned. "This doesn't mean you can plop down on the couch with a jar of peanut butter and a spoon," Pelkman said. "Calories still count."

The Buffalo researcher also advised people not to "chow down on bacon and double-cheese hamburgers." Pelkman pointed out that these foods contain lots of saturated fats that are known to increase the risk of heart disease.

Pelkman and her colleagues compared the effects of low-fat and moderate-fat diets in 53 overweight and obese men and women. For 6 weeks, people in the low-fat group consumed a diet in which 18 percent of total calories came from fat, while for those in the moderate-fat group 33 percent of calories came from fat.

For the first 6 weeks, the diets were designed to help people lose about 2 pounds per week. After that, participants were put on a 4-week weight-maintenance plan.

Both the low- and moderate-fat diets led to weight loss, but the moderate-fat diet had a more positive influence on markers of cardiovascular health, the researchers report in the American Journal of Clinical Nutrition (news - web sites).

Even though both groups of dieters experienced a drop in LDL, or "bad," cholesterol, the low-fat group also experienced a drop in levels of HDL, or "good," cholesterol after losing weight. HDL levels did not return to normal even after the 4-week weight-maintenance program.

In contrast, HDL levels remained steady in people who consumed a moderate-fat diet. They also experienced other improvements in cardiovascular health, including a decrease in triacylglycerol, a fatty substance linked to heart disease.

" These results show there are alternatives to a low-fat diet when it comes to losing weight and reducing your risk for heart disease," Pelkman said.

The researchers also point out that a moderate-fat diet may be easier to stick to in the long run than a low-fat plan.

To incorporate healthy monounsaturated fats into the diet, Pelkman recommended using olive or peanut oils to stir-fry vegetables and adding nuts and seeds to salads. She also noted that avocados and olives are rich sources of monounsaturated fats.

SOURCEL: American Journal of Clinical Nutrition, February 2004.